Tg(Zbtb7b-EGFP)WTRbo
Transgene Detail

Summary

• Symbol: Tg(Zbtb7b-EGFP)WTRbo
• Name: transgene insertion WT, Remy Bosselut
• MGI ID: MGI:6728845
• Synonyms: Thpok^GFP, ThPOK GFP BAC WT
• Transgene: Tg(Zbtb7b-EGFP)WTRbo Location: unknown
• Alliance: Tg(Zbtb7b-EGFP)WTRbo page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Using BAC RP23-64L17 with recombineering, an EGFP cDNA was inserted into the 5' end of exon 2 (the first coding exon). The loxP site flanked neomycin resistance gene cassette that was also inserted was removed through subsequent cre-mediated recombination. (J:141145)

Expression

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:141145 Wang L, et al., Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat Immunol. 2008 Oct;9(10):1122-30
• All: 4 reference(s)