Ppp1r3a^em1Wex
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppp1r3a^em1Wex
• Name: protein phosphatase 1, regulatory subunit 3A; endonuclease-mediated mutation 1, Xander Wehrens
• MGI ID: MGI:6728836
• Gene: Ppp1r3a Location: Chr6:14713976-14755273 bp, - strand Genetic Position: Chr6, 6.31 cM, cytoband A2
• Alliance: Ppp1r3a^em1Wex page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2 and 3. (J:304520)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppp1r3a Mutation: 57 strains or lines available

References

• Original: J:304520 Alsina KM, et al., Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation. Circulation. 2019 Aug 20;140(8):681-693
• All: 1 reference(s)