Tas1r3^{em1(Otop1)Csz}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tas1r3^{em1(Otop1)Csz}
• Name: taste receptor, type 1, member 3; endonuclease-mediated mutation 1, Charles S Zuker
• MGI ID: MGI:6728134
• Synonyms: T1R3-Otop1
• Gene: Tas1r3 Location: Chr4:155943725-155947810 bp, - strand Genetic Position: Chr4, 87.65 cM
• Alliance: Tas1r3^{em1(Otop1)Csz} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR/Cas genome editing technology was used to insert the coding sequence of murine Otop1 and a BGH polyA 3' in frame after the ATG start of the Tas1r3 ORF. (J:293042)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tas1r3 Mutation: 39 strains or lines available

References

• Original: J:293042 Zhang J, et al., Sour Sensing from the Tongue to the Brain. Cell. 2019 Oct 3;179(2):392-402.e15
• All: 1 reference(s)