Hcn3^em1Csz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hcn3^em1Csz
• Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 3; endonuclease-mediated mutation 1, Charles S Zuker
• MGI ID: MGI:6728131
• Synonyms: Hcn3^-
• Gene: Hcn3 Location: Chr3:89054082-89067538 bp, - strand Genetic Position: Chr3, 39.01 cM, cytoband F2
• Alliance: Hcn3^em1Csz page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas genome editing technology was used to generate a 79 bp deletion of genomic sequences in the Hcn3 gene, resulting in early termination after amino acid residue #43. (J:293042)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hcn3 Mutation: 24 strains or lines available

References

• Original: J:293042 Zhang J, et al., Sour Sensing from the Tongue to the Brain. Cell. 2019 Oct 3;179(2):392-402.e15
• All: 1 reference(s)