Meis2^tm1.1Zzz
Targeted Allele Detail

Summary

• Symbol: Meis2^tm1.1Zzz
• Name: Meis homeobox 2; targeted mutation 1.1, Zhuangzhi Zhang
• MGI ID: MGI:6726139
• Synonyms: Meis2^F
• Gene: Meis2 Location: Chr2:115693545-115896320 bp, - strand Genetic Position: Chr2, 58.28 cM
• Alliance: Meis2^tm1.1Zzz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306377
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct introduced an FRT site, splice acceptor, IRES sequence, lacZ reporter gene, FRT site, and loxP site. An additional loxP site was inserted downstream of exon 8. Flp-mediated recombination removed the reporter/selection cassette and left exon 8 floxed. (J:306377)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meis2 Mutation: 30 strains or lines available

References

• Original: J:306377 Yang L, et al., Transcriptional profiling reveals the transcription factor networks regulating the survival of striatal neurons. Cell Death Dis. 2021 Mar 12;12(3):262
• All: 2 reference(s)