Sox30^tm1Nju
Targeted Allele Detail

Summary

• Symbol: Sox30^tm1Nju
• Name: SRY (sex determining region Y)-box 30; targeted mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6724580
• Synonyms: Sox30^loxp
• Gene: Sox30 Location: Chr11:45871137-45908821 bp, + strand Genetic Position: Chr11, 27.49 cM
• Alliance: Sox30^tm1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307739
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct introduced between exon 2 and 3 LoxP-SA-IRES-GFP-NEO-STOP-PPS-LoxP cassette. (J:307739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox30 Mutation: 18 strains or lines available

References

• Original: J:307739 Han F, et al., Epigenetic Inactivation of SOX30 Is Associated with Male Infertility and Offers a Therapy Target for Non-obstructive Azoospermia. Mol Ther Nucleic Acids. 2020 Mar 6;19:72-83
• All: 1 reference(s)