Ly6g^{em1(dre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ly6g^{em1(dre/ERT2)Smoc}
• Name: lymphocyte antigen 6 family member G; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6724266
• Synonyms: Ly6g-2A-DreER, Ly6g-2A-DreERT2, Ly6g^{em1(2A-DreERT2)Smoc}
• Gene: Ly6g Location: Chr15:75027110-75030977 bp, + strand Genetic Position: Chr15, 34.29 cM, cytoband E1
• Alliance: Ly6g^{em1(dre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Ly6g^{em1(dre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ly6g (MGI:109440)

• Mutation details: A 2A-DreERT2 expression cassette was knocked into the Ly6g gene stop codon site via CRISPR/Cas mediated recombination. (J:238766, J:304636)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ly6g (mouse) Summary of all recombinase alleles driven by Ly6g. Alliance mouse Ly6g gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ly6g Mutation: 22 strains or lines available

References

• Original: J:304636 Han X, et al., A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. 2021 Feb 2
• All: 2 reference(s)