Gata4^tm1.1Ykaw
Targeted Allele Detail

Summary

• Symbol: Gata4^tm1.1Ykaw
• Name: GATA binding protein 4; targeted mutation 1.1, Yoshiya Kawaguchi
• MGI ID: MGI:6724014
• Synonyms: Gata4^tdTomato
• Gene: Gata4 Location: Chr14:63436371-63509141 bp, - strand Genetic Position: Chr14, 33.24 cM
• Alliance: Gata4^tm1.1Ykaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301269
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A td Tomato-pAPGK-Puro-pA replaced most of exon 1 after the first ATG of the Gata4 gene via homologous recombination in ES cells. Recombination removed the selection cassette. (J:301269)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata4 Mutation: 36 strains or lines available

References

• Original: J:301269 Sankoda N, et al., Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560
• All: 1 reference(s)