Usp28^em2Baz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp28^em2Baz
• Name: ubiquitin specific peptidase 28; endonuclease-mediated mutation 2, Hisham Bazzi
• MGI ID: MGI:6723825
• Gene: Usp28 Location: Chr9:48896675-48953817 bp, + strand Genetic Position: Chr9, 26.56 cM
• Alliance: Usp28^em2Baz page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 16 bp deletion in exon 2 (CTGCGAGAAATCACAG) using the gRNA AATCAGCTGCGAGAAATCAC. (J:306061)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp28 Mutation: 79 strains or lines available

References

• Original: J:306061 Damen M, et al., High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227
• All: 1 reference(s)