Mirc22^em1Zsg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mirc22^em1Zsg
• Name: microRNA cluster 22, including Mir23b through Mir24-1; endonuclease-mediated mutation 1, Shi-Gang Zhao
• MGI ID: MGI:6723810
• Gene: Mirc22 Location: Chr13:63448298-63449089 bp Genetic Position: Chr13, Syntenic

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mirc22^em1Zsg involves 3 genes/genome features (Mir23b, Mir27b, Mir24-1) View all
• CRISPR-targeting deleted 1009 bp encompassing the three microRNAs contained within the cluster. (J:306999)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc22 Mutation: 3 strains or lines available

References

• Original: J:306999 Jiang YH, et al., Loss of miR-23b/27b/24-1 Cluster Impairs Glucose Tolerance via Glycolysis Pathway in Mice. Int J Mol Sci. 2021 Jan 7;22(2):550
• All: 1 reference(s)