Chchd2^tm2Noha
Targeted Allele Detail

Summary

• Symbol: Chchd2^tm2Noha
• Name: coiled-coil-helix-coiled-coil-helix domain containing 2; targeted mutation 2, Nobutaka Hattori
• MGI ID: MGI:6720829
• Synonyms: CHCHD2 KO
• Gene: Chchd2 Location: Chr5:129910002-129916311 bp, - strand Genetic Position: Chr5, 68.26 cM
• Alliance: Chchd2^tm2Noha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307383
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 5.8-kb region that includes exons 13 was replaced by an FRT site flanked neomycin resistance gene cassette. (J:307383)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chchd2 Mutation: 6 strains or lines available

References

• Original: J:307383 Sato S, et al., Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice. Hum Mol Genet. 2021 Apr 30;30(6):443-453
• All: 1 reference(s)