Rbm8a^tm1.1Gan
Targeted Allele Detail

Summary

• Symbol: Rbm8a^tm1.1Gan
• Name: RNA binding motif protein 8a; targeted mutation 1.1, Lin Gan
• MGI ID: MGI:6720284
• Synonyms: Rbm8a^fl
• Gene: Rbm8a Location: Chr3:96537249-96541107 bp, + strand Genetic Position: Chr3, 41.93 cM, cytoband H3
• Alliance: Rbm8a^tm1.1Gan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306874
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac and C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 2-4 were flanked by loxP sites and an FRT-flanked neomycin-resistance cassette (PGK-neo) was inserted down stream of exon 4 inside the loxP sites. The selection cassette was removed via cre-mediated recombination leaving exons 2-4 floxed. (J:306874)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm8a Mutation: 6 strains or lines available

References

• Original: J:306874 McSweeney C, et al., Full function of exon junction complex factor, Rbm8a, is critical for interneuron development. Transl Psychiatry. 2020 Nov 5;10(1):379
• All: 3 reference(s)