Vcan^tm1.2Hwat
Targeted Allele Detail

Summary

• Symbol: Vcan^tm1.2Hwat
• Name: versican; targeted mutation 1.2, Hideto Watanabe
• MGI ID: MGI:6720270
• Synonyms: Vcan^RC
• Gene: Vcan Location: Chr13:89803431-89890628 bp, - strand Genetic Position: Chr13, 45.5 cM
• Alliance: Vcan^tm1.2Hwat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165936
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette leaving exon 2 floxed. Cre mediated recombination removed exons 2. (J:165936, J:298707)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vcan Mutation: 166 strains or lines available

References

• Original: J:165936 Choocheep K, et al., Versican facilitates chondrocyte differentiation and regulates joint morphogenesis. J Biol Chem. 2010 Jul 2;285(27):21114-25
• All: 3 reference(s)