Elavl2^tm1.1Ysa
Targeted Allele Detail

Summary

• Symbol: Elavl2^tm1.1Ysa
• Name: ELAV like RNA binding protein 1; targeted mutation 1.1, Yumiko Saga
• MGI ID: MGI:6720235
• Synonyms: Elavl2^floxdeltaNeo
• Gene: Elavl2 Location: Chr4:91139000-91289022 bp, - strand Genetic Position: Chr4, 42.36 cM
• Alliance: Elavl2^tm1.1Ysa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282136
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: By homologous recombination targeting in ES cells, the exon 3 (ENSMUSE00001275521) including the start codon was flanked by loxP sequences and was followed by the Pgk-neo cassette flanked by Frt sequences. The Pgk-neo cassette was removed by crossing with Rosa-Flp mice. (J:282136)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elavl2 Mutation: 52 strains or lines available

References

• Original: J:282136 Kato Y, et al., ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles. EMBO Rep. 2019 Dec 5;20(12):e48251
• All: 1 reference(s)