Tacr3^tm1.2Wspn
Targeted Allele Detail

Summary

• Symbol: Tacr3^tm1.2Wspn
• Name: tachykinin receptor 3; targeted mutation 1.2, Will Spooren
• MGI ID: MGI:6719361
• Gene: Tacr3 Location: Chr3:134534768-134640340 bp, + strand Genetic Position: Chr3, 62.47 cM, cytoband H2
• Alliance: Tacr3^tm1.2Wspn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306439
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct introduced a loxP site 68 bp upstream of exon 1 and a floxed neomycin resistance cassette downstream of exon 1. Cre-mediated recombination removed the selection cassette and left exon 1 floxed. (J:306439)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tacr3 Mutation: 34 strains or lines available

References

• Original: J:306439 Nordquist RE, et al., Cognitive performance in neurokinin 3 receptor knockout mice. Psychopharmacology (Berl). 2008 Jun;198(2):211-20
• All: 1 reference(s)