Prss35^em1Irc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss35^em1Irc
• Name: serine protease 35; endonuclease-mediated mutation 1, Inflammation Research Center
• MGI ID: MGI:6719080
• Synonyms: PRSS35 KO
• Gene: Prss35 Location: Chr9:86625702-86640496 bp, + strand Genetic Position: Chr9, 46.58 cM
• Alliance: Prss35^em1Irc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: using the CRISPR/Cas9 system an allele with a deletion of 1870 bp (chr9+: 86754911-86756780) removing all coding sequences of the Prss35 gene was generated. (J:306287)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prss35 Mutation: 29 strains or lines available

References

• Original: J:306287 Van Hove L, et al., Fibrotic enzymes modulate wound-induced skin tumorigenesis. EMBO Rep. 2021 May 5;22(5):e51573
• All: 1 reference(s)