Egln3^tm1Ago
Targeted Allele Detail

Summary

• Symbol: Egln3^tm1Ago
• Name: egl-9 family hypoxia-inducible factor 3; targeted mutation 1, Ananda Goldrath
• MGI ID: MGI:6718448
• Synonyms: Egln3-YFP
• Gene: Egln3 Location: Chr12:54225767-54250646 bp, - strand Genetic Position: Chr12, 22.9 cM
• Alliance: Egln3^tm1Ago page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306906
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The YFP reporter gene was inserted into exon 1 at or after the start codon of the host gene, disrupting the Egln3 CDS. (J:306906)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Egln3 Mutation: 26 strains or lines available

References

• Original: J:306906 Zhu B, et al., Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection. Immunity. 2021 Apr 28
• All: 1 reference(s)