Gnpat^tm1.2Fudi
Targeted Allele Detail

Summary

• Symbol: Gnpat^tm1.2Fudi
• Name: glyceronephosphate O-acyltransferase; targeted mutation 1.2, Fudi Wang
• MGI ID: MGI:6717453
• Gene: Gnpat Location: Chr8:125589772-125616796 bp, + strand Genetic Position: Chr8, 72.81 cM
• Alliance: Gnpat^tm1.2Fudi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306667
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J x 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4 and an FRT-flanked pGK-neomcyin selection cassette and a second loxP site were inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and cre-mediated recombination deleted exon 4. (J:306667)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnpat Mutation: 42 strains or lines available

References

• Original: J:306667 An P, et al., Gnpat does not play an essential role in systemic iron homeostasis in murine model. J Cell Mol Med. 2020 Apr;24(7):4118-4126
• All: 1 reference(s)