Tg(Vil1-Lyz1)#Ngao
Transgene Detail

Summary

• Symbol: Tg(Vil1-Lyz1)#Ngao
• Name: transgene insertion, Nan Gao
• MGI ID: MGI:6717274
• Synonyms: Villin-Lyz1^TG
• Transgene: Tg(Vil1-Lyz1)#Ngao Location: unknown
• Alliance: Tg(Vil1-Lyz1)#Ngao page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Vil1-Lyz1)#Ngao expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lyz1 (MGI:96902)	mouse promoter and cDNA

• Mutation details: In this transgene construct, the CDS from a mouse lysozyme 1 cDNA was placed between the mouse villin 1 promoter and SV40 polyA signal sequences to drive expression of lysozyme in intestinal epithelial cells. Two separate mouse lines were maintained. (J:306653)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:306653 Yu S, et al., Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine. Immunity. 2020 Aug 18;53(2):398-416.e8
• All: 1 reference(s)