Trp53^tm2359Arte
Targeted Allele Detail

Summary

• Symbol: Trp53^tm2359Arte
• Name: transformation related protein 53; targeted mutation 2359, TaconicArtemis
• MGI ID: MGI:6716027
• Synonyms: Trp53^{tm2359(R245W_T2A-EGFP)Arte}
• Gene: Trp53 Location: Chr11:69471185-69482699 bp, + strand Genetic Position: Chr11, 42.83 cM, cytoband B2-C
• Alliance: Trp53^tm2359Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169366
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The targeting construct altered the coding sequence to produce the amino acid substitution of arginine with tryptophan at position 245 (p.R245W) and inserted a T2A sequence and EGFP reporter gene. (J:169366)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Trp53 Mutation: 237 strains or lines available

References

• Original: J:169366 MouseBook^TM, Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013
• All: 2 reference(s)