Ltbr^em1Htaka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ltbr^em1Htaka
• Name: lymphotoxin B receptor; endonuclease-mediated mutation 1, Hiroshi Takayanagi
• MGI ID: MGI:6715656
• Synonyms: Ltbr^flox
• Gene: Ltbr Location: Chr6:125283534-125290848 bp, - strand Genetic Position: Chr6, 59.32 cM
• Alliance: Ltbr^em1Htaka page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites in introns 2 and 5. (J:306398)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ltbr Mutation: 46 strains or lines available

References

• Original: J:306398 Nitta T, et al., Fibroblasts as a source of self-antigens for central immune tolerance. Nat Immunol. 2020 Oct;21(10):1172-1180
• All: 1 reference(s)