Tg(Myh6-NFE2L2)212A5Cuit
Transgene Detail

Summary

• Symbol: Tg(Myh6-NFE2L2)212A5Cuit
• Name: transgene insertion 212A5, Taixing Cui
• MGI ID: MGI:6715223
• Synonyms: Nrf2^ctg
• Transgene: Tg(Myh6-NFE2L2)212A5Cuit Location: unknown
• Alliance: Tg(Myh6-NFE2L2)212A5Cuit page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-NFE2L2)212A5Cuit expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  NFE2L2 (4780)

  Nfe2l2

  (MGI:108420)

• Tg(Myh6-NFE2L2)212A5Cuit expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myh6 (MGI:97255)

• Mutation details: The transgene contains the full-length human NFE2L2 cDNA cloned into a vector containing the alpha-myosin heavy chain (alpha-MHC) promoter. Line 212A5 was generated. (J:224956)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:224956 Wang W, et al., Nrf2 enhances myocardial clearance of toxic ubiquitinated proteins. J Mol Cell Cardiol. 2014 Jul;72:305-15
• All: 1 reference(s)