Dnm2^tm3.1Ics
Targeted Allele Detail

Summary

• Symbol: Dnm2^tm3.1Ics
• Name: dynamin 2; targeted mutation 3.1, Mouse Clinical Institute
• MGI ID: MGI:6715207
• Synonyms: Dnm2S619L
• Gene: Dnm2 Location: Chr9:21336204-21419055 bp, + strand Genetic Position: Chr9, 7.79 cM
• Alliance: Dnm2^tm3.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306120
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: Serine codon 619 (TCG) in exon 17 was changed to leucine (CTG) (p.S619L). The loxP site flanked neomycin resistance gene and protoamine promoter-driven cre gene cassette that was inserted auto-excised. (J:306120)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnm2 Mutation: 101 strains or lines available

References

• Original: J:306120 Birling M-C, Dnm2 mutation. MGI Direct Data Submission. 2021
• All: 1 reference(s)