Gt(ROSA)26Sor^{tm1.1(GFP)Tahi}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(GFP)Tahi}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Tatsumi Hirata
• MGI ID: MGI:6712692
• Synonyms: R26-TRE-memGFP(KI), ROSA26-TRE^mGFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(GFP)Tahi} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288786
• Parent Cell Line: B6-3i/HK3i (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Targeted (Inducible, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The tetracycline response element (TRE) was connected to a GFP gene containing a palmitoylation sequence of GAP43 N terminally, and the construct was flanked by 2xcHS4 insulators. A targeting vector, the 2xcHS4 TRE-mGFP with an frt-flanked neomycin resistant gene was introduced into the HK3i embryonic stem cells derived from C57BL/6. (J:288786)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1060 strains or lines available

References

• Original: J:288786 Hirata T, et al., A Novel Birthdate-Labeling Method Reveals Segregated Parallel Projections of Mitral and External Tufted Cells in the Main Olfactory System. eNeuro. 2019 Nov/Dec;6(6):ENEURO.0234-19.2019
• All: 1 reference(s)