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B2mb
Spontaneous Allele Detail
Nomenclature
Symbol: B2mb
Name: beta-2 microglobulin; b variant
MGI ID: MGI:6711994
Gene: B2m  Location: Chr2:121978168-121983563 bp, + strand  Genetic Position: Chr2, 60.55 cM, cytoband F1-F3
Mutation
origin
Strain of Origin:  C57BL
Mutation
description
Allele Type:    Spontaneous (Not Applicable)
Mutation:    Nucleotide substitutions
 
Mutation detailsThe b variant is runs faster than the a variant on SDS PAGE and was found to have an alanine at amino acid position 85. This allele is found in the C57BL strain family including C57BL/6, C57BL/10, C57L/J, C57BR/cdJ, as well as CAST/Ei, but not in C58/J, which has the a variant. (J:6520, J:7014)
Inheritance:    Codominant
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any B2m Mutation:  117 strains or lines available
References
Original:  J:7014 Michaelson J, Genetics of beta-2 microglobulin in the mouse. Immunogenetics. 1983;17(3):219-60
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory