Rcn3^tm2.1Rzm
Targeted Allele Detail

Summary

• Symbol: Rcn3^tm2.1Rzm
• Name: reticulocalbin 3, EF-hand calcium binding domain; targeted mutation 2.1, Runlin Z Ma
• MGI ID: MGI:6696450
• Synonyms: Rcn3^fl
• Gene: Rcn3 Location: Chr7:44732337-44741645 bp, - strand Genetic Position: Chr7, 29.11 cM
• Alliance: Rcn3^tm2.1Rzm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278774
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exon 3. The frt-flanked neomycin selection cassette was deleted via FLP1 mediated recombination in the germline. (J:278774)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rcn3 Mutation: 15 strains or lines available

References

• Original: J:278774 Jin J, et al., Reticulocalbin 3 Deficiency in Alveolar Epithelium Exacerbated Bleomycin-induced Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2018 Sep;59(3):320-333
• All: 2 reference(s)