Ackr3^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Ackr3^tm1.1Geno
• Name: atypical chemokine receptor 3; targeted mutation 1.1, Genoway
• MGI ID: MGI:6696395
• Synonyms: ACKR3^fl
• Gene: Ackr3 Location: Chr1:90131702-90143446 bp, + strand Genetic Position: Chr1, 45.28 cM
• Alliance: Ackr3^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:299944
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 2 was flanked by loxP sites and an frt-flanked neomycin selection cassette was inserted 3' to exon 2. The neomycin selection cassette was removed via FLP1-mediated recombination in the germline. (J:299944)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ackr3 Mutation: 34 strains or lines available

References

• Original: J:299944 Radice E, et al., Marginal Zone Formation Requires ACKR3 Expression on B Cells. Cell Rep. 2020 Aug 4;32(5):107951
• All: 2 reference(s)