P3h3^tm1.1Hpb
Targeted Allele Detail

Summary

• Symbol: P3h3^tm1.1Hpb
• Name: prolyl 3-hydroxylase 3; targeted mutation 1.1, Hans Peter Bachinger
• MGI ID: MGI:6696380
• Synonyms: Leprel2^-
• Gene: P3h3 Location: Chr6:124818052-124834680 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: P3h3^tm1.1Hpb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304810
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A PGK-neo selection cassette flanked by FRT sites was inserted downstream of exon 1, and exon 1 was flanked by loxP sites. The targeted locus was deleted via Cre- amd FLP-mediated recombination. (J:304810)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P3h3 Mutation: 46 strains or lines available

References

• Original: J:304810 Ishikawa Y, et al., Type I and type V procollagen triple helix use different subsets of the molecular ensemble for lysine post-translational modifications in the rER. J Biol Chem. 2021 Feb 22;:100453
• All: 1 reference(s)