Gt(ROSA)26Sor^tm20Sia
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm20Sia
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 20, Shinichi Aizawa
• MGI ID: MGI:6695735
• Synonyms: PLEKHA7-EGFP, R26-PHA7-EGFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm20Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304604
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A vector, which contains (5' to 3') a splice acceptor, floxed neo/stop cassette, human PLEKHA7 EGFP, self-cleavage 2A peptide sequence, endoplasmic reticulum signal peptide sequence, EGFP, and GPI anchor sequence, was inserted into the locus. (J:304604)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:304604 Shioi G, et al., Apical constriction in distal visceral endoderm cells initiates global, collective cell rearrangement in embryonic visceral endoderm to form anterior visceral endoderm. Dev Biol. 2017 Sep 1;429(1):20-30
• All: 2 reference(s)