Ngfr^tm1.1Utsw
Targeted Allele Detail

Summary

• Symbol: Ngfr^tm1.1Utsw
• Name: nerve growth factor receptor (TNFR superfamily, member 16); targeted mutation 1.1, University of Texas Southwestern Medical Center
• MGI ID: MGI:6694130
• Synonyms: p75^F
• Gene: Ngfr Location: Chr11:95459644-95478524 bp, - strand Genetic Position: Chr11, 59.01 cM
• Alliance: Ngfr^tm1.1Utsw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254788
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the selection cassette and left exon 3 floxed. (J:254788)

Expression

In Mice Carrying this Mutation:

54 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ngfr Mutation: 32 strains or lines available

References

• Original: J:254788 Chen Z, et al., p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling. Cell Rep. 2017 Oct 17;21(3):707-720
• All: 1 reference(s)