Gstk1^tm1.1Fliu
Targeted Allele Detail

Summary

• Symbol: Gstk1^tm1.1Fliu
• Name: glutathione S-transferase kappa 1; targeted mutation 1.1 Feng Liu
• MGI ID: MGI:6693443
• Synonyms: DsbA-L^loxP
• Gene: Gstk1 Location: Chr6:42222869-42227375 bp, + strand Genetic Position: Chr6, 20.52 cM
• Alliance: Gstk1^tm1.1Fliu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246798
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exons 1-3. The frt-flanked neomycin selection cassette was removed via Flp1-mediated recombination. (J:246798)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gstk1 Mutation: 18 strains or lines available

References

• Original: J:246798 Chen H, et al., Hepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance. FASEB J. 2017 Jun;31(6):2314-2326
• All: 7 reference(s)