Acvr1btm1.1Cfi
Targeted Allele Detail
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Symbol: |
Acvr1btm1.1Cfi |
Name: |
activin A receptor, type 1B; targeted mutation 1.1, Carlos F Ibanez |
MGI ID: |
MGI:6690707 |
Synonyms: |
Alk4fl |
Gene: |
Acvr1b Location: Chr15:101071953-101111565 bp, + strand Genetic Position: Chr15, 56.48 cM
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Alliance: |
Acvr1btm1.1Cfi page
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Germline Transmission: |
Earliest citation of germline transmission:
J:282137
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted flanking exons 5 and 6, encoding essential regions of the ALK4 kinase domain. The neomycin selection cassette was deleted via FLP1-mediated recombination in the germline,
(J:282137)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Acvr1b Mutation: |
36 strains or lines available
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Original: |
J:282137 Gongrich C, et al., ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons. J Cell Biol. 2020 Jan 6;219(1) |
All: |
1 reference(s) |
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