Tax1bp3^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Tax1bp3^{tm1c(EUCOMM)Hmgu}
• Name: Tax1 (human T cell leukemia virus type I) binding protein 3; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6508042
• Gene: Tax1bp3 Location: Chr11:73067909-73072872 bp, + strand Genetic Position: Chr11, 45.25 cM
• Alliance: Tax1bp3^{tm1c(EUCOMM)Hmgu} page
• IMPC: Tax1bp3 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The L1L2_Bact_P cassette was inserted at a position on Chromosome 11 upstream of exon 2. The cassette is composed of a FRT site followed by a lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance (neo) gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 4. Flp-mediated recombination removed the FRT-flanked neo cassette and lacZ reporter. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tax1bp3 Mutation: 11 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 2 reference(s)