Arhgef7^tm1.1Awp
Targeted Allele Detail

Summary

• Symbol: Arhgef7^tm1.1Awp
• Name: Rho guanine nucleotide exchange factor; targeted mutation 1.1, Andreas W Puschel
• MGI ID: MGI:6508035
• Synonyms: Arhgef7^flox
• Gene: Arhgef7 Location: Chr8:11778053-11885219 bp, + strand Genetic Position: Chr8, 5.73 cM
• Alliance: Arhgef7^tm1.1Awp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278009
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 4 is flanked with loxP sites and an frt-flanked neomycin selection cassette. The neomycin selection cassette was removed via FLP1-mediated recombination in the germline. (J:278009)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgef7 Mutation: 53 strains or lines available

References

• Original: J:278009 Lopez Tobon A, et al., The guanine nucleotide exchange factor Arhgef7/betaPix promotes axon formation upstream of TC10. Sci Rep. 2018 Jun 11;8(1):8811
• All: 1 reference(s)