Rxfp3^em2J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rxfp3^em2J
• Name: relaxin family peptide receptor 3; endonuclease-mediated mutation 2, Jackson
• MGI ID: MGI:6506220
• Gene: Rxfp3 Location: Chr15:11033803-11038054 bp, - strand Genetic Position: Chr15, 5.42 cM
• Alliance: Rxfp3^em2J page

Mutation origin

• Strain of Origin: C57BL/6NJ

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: This allele was generated by inserting a 2005 bp conditional by inversion (COIN) cassette containing a rabbit beta-globin polyA site, EGFP and inverted lox site variants (lox71/lox66) in inverse orientation into exon1. This is functionally a wild-type allele, but cre-mediated recombination will yield a null allele detectable by expression of enhanced green fluorescent protein. (J:299754)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rxfp3 Mutation: 22 strains or lines available

References

• Original: J:299754 Farris MH, et al., Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands. BMC Genomics. 2020 Dec 2;21(1):856
• All: 1 reference(s)