About   Help   FAQ
Endonuclease-mediated Allele Detail
Symbol: Rxfp3em2J
Name: relaxin family peptide receptor 3; endonuclease-mediated mutation 2, Jackson
MGI ID: MGI:6506220
Gene: Rxfp3  Location: Chr15:11033803-11038054 bp, - strand  Genetic Position: Chr15, 5.42 cM
Strain of Origin:  C57BL/6NJ
Allele Type:    Endonuclease-mediated (Conditional ready, Reporter)
Mutation:    Insertion
Mutation detailsThis allele was generated by inserting a 2005 bp conditional by inversion (COIN) cassette containing a rabbit beta-globin polyA site, EGFP and inverted lox site variants (lox71/lox66) in inverse orientation into exon1. This is functionally a wild-type allele, but cre-mediated recombination will yield a null allele detectable by expression of enhanced green fluorescent protein. (J:299754)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rxfp3 Mutation:  14 strains or lines available
Original:  J:299754 Farris MH, et al., Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands. BMC Genomics. 2020 Dec 2;21(1):856
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.17
The Jackson Laboratory