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Rxfp3em2J
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Rxfp3em2J
Name: relaxin family peptide receptor 3; endonuclease-mediated mutation 2, Jackson
MGI ID: MGI:6506220
Gene: Rxfp3  Location: Chr15:11033803-11038054 bp, - strand  Genetic Position: Chr15, 5.42 cM
Mutation
origin
Strain of Origin:  C57BL/6NJ
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsThis allele was generated by inserting a 2005 bp conditional by inversion (COIN) cassette containing a rabbit beta-globin polyA site, EGFP and inverted lox site variants (lox71/lox66) in inverse orientation into exon1. This is functionally a wild-type allele, but cre-mediated recombination will yield a null allele detectable by expression of enhanced green fluorescent protein. (J:299754)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rxfp3 Mutation:  14 strains or lines available
References
Original:  J:299754 Farris MH, et al., Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands. BMC Genomics. 2020 Dec 2;21(1):856
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory