Ctnnb1^em1Hhx
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ctnnb1^em1Hhx
• Name: catenin beta 1; endonuclease-mediated mutation 1, Hai-Hui Xue
• MGI ID: MGI:6502874
• Synonyms: Ctnnb1^fl
• Gene: Ctnnb1 Location: Chr9:120762466-120789573 bp, + strand Genetic Position: Chr9, 72.19 cM
• Alliance: Ctnnb1^em1Hhx page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Two LoxP cassettes were inserted into introns 1 and 14 via CRISPR genome editing technology, flanking exons 2 to 14 of the gene. (J:294998)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ctnnb1 Mutation: 47 strains or lines available

References

• Original: J:294998 Zhao X, et al., beta-catenin and gamma-catenin are dispensable for T lymphocytes and AML leukemic stem cells. Elife. 2020 Aug 21;9:e55360
• All: 1 reference(s)