Nfil3^tm1Brad
Targeted Allele Detail

Summary

• Symbol: Nfil3^tm1Brad
• Name: nuclear factor, interleukin 3, regulated; targeted mutation 1, Hugh Brady
• MGI ID: MGI:6502681
• Synonyms: Nfil3^f
• Gene: Nfil3 Location: Chr13:53121245-53135109 bp, - strand Genetic Position: Chr13, 27.68 cM
• Alliance: Nfil3^tm1Brad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152774
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding region and a loxP site flanked neomycin resistance gene cassette was inserted downstream of the coding exon. (J:152774)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfil3 Mutation: 33 strains or lines available

References

• Original: J:152774 Gascoyne DM, et al., The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol. 2009 Oct;10(10):1118-24
• All: 2 reference(s)