Cgn^tm1.2Citi
Targeted Allele Detail

Summary

• Symbol: Cgn^tm1.2Citi
• Name: cingulin; targeted mutation 1.2, Sandra Citi
• MGI ID: MGI:6502146
• Synonyms: CGN^fl
• Gene: Cgn Location: Chr3:94667376-94693826 bp, - strand Genetic Position: Chr3, 40.74 cM
• Alliance: Cgn^tm1.2Citi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:299889
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A floxed neomycin resistance cassette was inserted downstream of exon 1. The neomycin resistance cassette was removed via Cre-mediated recombination in the germline, leaving loxP sites flanking exon 1. (J:200284)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cgn Mutation: 58 strains or lines available

References

• Original: J:299889 Zhuravleva K, et al., The tight junction protein cingulin regulates the vascular response to burn injury in a mouse model. Microvasc Res. 2020 Nov;132:104067
• All: 2 reference(s)