Gt(ROSA)26Sor^{tm1(Hoxa11)Makm}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Hoxa11)Makm}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Marie Kmita
• MGI ID: MGI:6500988
• Synonyms: R26^A11d, Rosa26^Hoxa11, Rosa^Hoxa11
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Hoxa11)Makm} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239414
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector introduced into the locus a splice acceptor site, floxed neomycin resistance and triple polyadylation sequence (STOP), Hoxa11 gene, IRES sequence, and EGFP reporter gene. (J:239414)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:239414 Kherdjemil Y, et al., Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state. Nature. 2016 Nov 03;539(7627):89-92
• All: 2 reference(s)