Ace2^em1Pbmj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ace2^em1Pbmj
• Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 1, Paul McCray
• MGI ID: MGI:6491923
• Synonyms: Ace2^H353K
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^em1Pbmj page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 endonuclease-mediated genome editing is used to create an amino acid substitution at position 353 (histidine to lysine, H353K, CAC to AAA) in exon 8 (isoform Ace2-201). The mutation was confirmed by sequencing. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 72 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)