Phb2^em1Blev
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phb2^em1Blev
• Name: prohibitin 2; endonuclease-mediated mutation 1, Beth Levine
• MGI ID: MGI:6479051
• Synonyms: Phb2mLIR KI
• Gene: Phb2 Location: Chr6:124689299-124693913 bp, + strand Genetic Position: Chr6, 59.17 cM
• Alliance: Phb2^em1Blev page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR/cas9 genome editing is used to introduce the Y121A (TAC to GCG) and L124A (CTA to GCC) mutations into the LC3-interacting region in exon 4. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Phb2 Mutation: 22 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)