Fmr1nb^m1
Spontaneous Allele Detail

Summary

• Symbol: Fmr1nb^m1
• Name: Fmr1 neighbor; mutation 1
• MGI ID: MGI:6477935
• Gene: Fmr1nb Location: ChrX:67805460-67848167 bp, + strand Genetic Position: ChrX, 34.86 cM
• Alliance: Fmr1nb^m1 page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: This allele represents two point mutations that are found in the PWD and PWK strains: chrX:g.68762025C>G (minor variant of SNP rs29049709; changes codon 31 from threonine to arginine (p.T31R)) and 68769064T>A (minor variant of SNP rs29049158; changes codon 162 from isoleucine to lysine (p.I162K)) (GRCm38 coordinates). (J:292550)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fmr1nb Mutation: 4 strains or lines available

References

• Original: J:292550 Morimoto K, et al., Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis. Sci Rep. 2020 Jun 3;10(1):9060
• All: 1 reference(s)