Eml1^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Eml1^tm1.1Ics
• Name: echinoderm microtubule associated protein like 1; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:6473553
• Gene: Eml1 Location: Chr12:108337265-108505835 bp, + strand Genetic Position: Chr12, 59.46 cM
• Alliance: Eml1^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:294769
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 8 was flanked by loxP sites. A neomycin selection cassette flanked by FRT sites was inserted upstream of the second loxP site. Flp-mediated recombination removed the selection marker. (J:294769)

Expression

In Mice Carrying this Mutation:

42 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eml1 Mutation: 45 strains or lines available

References

• Original: J:294769 Collins SC, et al., The neuroanatomy of Eml1 knockout mice, a model of subcortical heterotopia. J Anat. 2019 Sep;235(3):637-650
• All: 3 reference(s)