Eed^tm1.1Homy
Targeted Allele Detail

Summary

• Symbol: Eed^tm1.1Homy
• Name: embryonic ectoderm development; targeted mutation 1.1, Hiroaki Honda
• MGI ID: MGI:6473296
• Synonyms: Eed^tm1Homy
• Gene: Eed Location: Chr7:89603862-89630184 bp, - strand Genetic Position: Chr7, 50.42 cM
• Alliance: Eed^tm1.1Homy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250153
• Parent Cell Line: KY1.1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 6 was floxed. Flp-mediated recombination removed the selection cassette. (J:250153)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eed Mutation: 116 strains or lines available

References

• Original: J:250153 Ikeda K, et al., Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency. Sci Rep. 2016 Jul 19;6:29454
• All: 1 reference(s)