Igfbp2^em2Ntang
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igfbp2^em2Ntang
• Name: insulin-like growth factor binding protein 2; endonuclease-mediated mutation 2, Nan Tang
• MGI ID: MGI:6472831
• Gene: Igfbp2 Location: Chr1:72863662-72891633 bp, + strand Genetic Position: Chr1, 36.94 cM
• Alliance: Igfbp2^em2Ntang page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Deletion
• Mutation details: The allele was generated by deleting exon 1 of the endogenous mouse Igfbp2 gene via Cas9/RNA mediated gene targeting in zygotes. (J:260595)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igfbp2 Mutation: 23 strains or lines available

References

• Original: J:260595 Wang Y, et al., Pulmonary alveolar type I cell population consists of two distinct subtypes that differ in cell fate. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2407-2412
• All: 1 reference(s)