Gt(ROSA)26Sor^{tm2(Dmrta2)Zark}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(Dmrta2)Zark}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, David Zarkower
• MGI ID: MGI:6471096
• Synonyms: Dmrt5^Tg
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(Dmrta2)Zark} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254118
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(Dmrta2)Zark} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Dmrta2 (MGI:2653629)

• Mutation details: The targeting vector contains a loxP-NEO STOP-loxP, the mouse Dmrta2 coding sequence, and an IRES-EGFP and inserted in the ROSA26 locus. (J:254118)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:254118 De Clercq S, et al., DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation. Cereb Cortex. 2018 Feb 1;28(2):493-509
• All: 1 reference(s)