Bmi1^tm1.1Hko
Targeted Allele Detail

Summary

• Symbol: Bmi1^tm1.1Hko
• Name: Bmi1 polycomb ring finger oncogene; targeted mutation 1.1, Haruhiko Koseki
• MGI ID: MGI:6470926
• Gene: Bmi1 Location: Chr2:18681953-18691440 bp, + strand Genetic Position: Chr2, 12.9 cM
• Alliance: Bmi1^tm1.1Hko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271511
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A floxed allele was generated. (J:271511)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bmi1 Mutation: 31 strains or lines available

References

• Original: J:271511 Cohen I, et al., PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification. Cell Stem Cell. 2018 May 3;22(5):726-739.e7
• All: 2 reference(s)