Neurog3^tm4Ggu
Targeted Allele Detail

Summary

• Symbol: Neurog3^tm4Ggu
• Name: neurogenin 3; targeted mutation 4, Guoqiang Gu
• MGI ID: MGI:6470699
• Synonyms: Neurog3^(HA.LCA)Ggu
• Gene: Neurog3 Location: Chr10:61968869-61970542 bp, + strand Genetic Position: Chr10, 32.35 cM, cytoband B4
• Alliance: Neurog3^tm4Ggu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296396
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector contains a 5.5 kb 5 arm and a 3.5 kb 3arm. Lox71 and Lox2272 sites were inserted flanking the gene, where the cDNA was replaced with that encoding for an HA-tagged Ngn3 protein. The vector also contains a FRT-flanked Pgk-Puro-deltaTK cassette for positive selection by puromycin (targeting events) and negative selection by ganciclovir (RMCE events). (J:296396)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Neurog3 Mutation: 21 strains or lines available

References

• Original: J:296396 Vanderbilt University, Labnodes. 2020
• All: 1 reference(s)