Opcml^tm1Pagr
Targeted Allele Detail

Summary

• Symbol: Opcml^tm1Pagr
• Name: opioid binding protein/cell adhesion molecule-like; targeted mutation 1, Paul Grossfeld
• MGI ID: MGI:6469746
• Synonyms: OPCML^f-neo
• Gene: Opcml Location: Chr9:27702071-28836706 bp, + strand Genetic Position: Chr9, 13.73 cM
• Alliance: Opcml^tm1Pagr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:294154
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 1 and a second loxP site plus an FRT site flanked neomycin resistance gene into intron 2. This creates a conditional-ready allele with exon 2 floxed. (J:294154)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Opcml Mutation: 33 strains or lines available

References

• Original: J:294154 Ye M, et al., Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects. Am J Med Genet A. 2014 Apr;164A(4):966-74
• All: 1 reference(s)