Otx1^{tm6(cre/ERT)Asim}
Targeted Allele Detail

Summary

• Symbol: Otx1^{tm6(cre/ERT)Asim}
• Name: orthodenticle homeobox 1; targeted mutation 6, Antonio Simeone
• MGI ID: MGI:6468494
• Synonyms: Otx1-CreER
• Gene: Otx1 Location: Chr11:21944764-21952897 bp, - strand Genetic Position: Chr11, 14.1 cM
• Alliance: Otx1^{tm6(cre/ERT)Asim} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Inducible, Null/knockout, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Otx1^{tm6(cre/ERT)Asim} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Otx1 (MGI:97450)

• The Otx1 allele is replaced with cre/ERT inducible recombinase fusion. (J:82809)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Otx1 (mouse) Summary of all recombinase alleles driven by Otx1. Alliance mouse Otx1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Otx1 Mutation: 86 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)